Celiac Disease

Discussing the latest advances in celiac disease

August 27th, 2015 · Leave a Comment

Breast Feeding and Gluten Introduction: What Research Tells Us

By Kanaaz Pereira Kanaaz Pereira

For patients with celiac disease, conceiving, delivering, and nursing healthy babies are not insurmountable challenges. Past research has led to the hypothesis that infant feeding practices and early or delayed introduction to gluten are key to the development of celiac disease. However, two recent studies published in the American Journal of Gastroenterology, co-authored by Joseph A. Murray, M.D., of Mayo Clinic in Rochester, Minn., found that the timing of gluten introduction — whether early or late in the first year of life — made no difference to the subsequent development of celiac disease.

While disappointing, these results should encourage the study of other risk factors such as intrauterine  exposures and environmental influences, including drug exposure and microbial infections. Given that celiac disease can develop at any age, it is imperative to study genetic background so as to develop future intervention strategies. With careful attention to diet, mother and baby can enjoy healthy lives.

Read the full study online here.

For more information about celiac disease, visit mayoclinic.org/celiac disease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Tags: American Journal of Gastroenterology, breast feeding, celiac disease, gluten, Joseph Murray

August 15th, 2015 · Leave a Comment

Can Enzymes Help Celiac Disease Patients from Gluten Exposure?

By Kanaaz Pereira Kanaaz Pereira

For patients with celiac disease, a gluten-free diet is the only treatment option currently. The diet requires total elimination of gluten, a protein found in wheat, barley, and rye, which when ingested can cause an autoimmune reaction, resulting in mucosal damage to the small intestine. Joseph Murray, M.D., a gastroenterologist at Mayo Clinic shares his expertise with the National Foundation for Celiac Awareness (NFCA), and provides answers to questions on enzymes, and the current status of some celiac disease therapies.

As diligent as celiacs can be, avoiding gluten can be a challenge, and slip-ups can happen. There are numerous pills, enzymes, and other products being marketed to provide some protection against accidental gluten exposure for people with celiac disease. These treatments are not intended to replace a gluten-free diet, but claim to reduce the reaction to small amounts of unintentionally ingested gluten by breaking down the protein in gluten. While there's some evidence that this theory may eventually prove true, there's no evidence that the enzymes marketed over-the-counter right now have any special action against gluten. Dr. Murray emphasizes that, “It is vitally important that patients with celiac disease do not use any of these preparations that are being touted for reducing gluten. They have no proven benefit for patients with celiac disease." 

Fortunately however, researchers are studying a variety of ways to identify and develop new treatment options. "People with celiac disease need to be patient as these can often take many years to put together all of the evidence to show they are both safe and effective.”

Read the full interview here.

For more information about celiac disease, visit mayoclinic.org/celiac disease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

 

Tags: celiac disease, enzyme, Gluten Free Diet, Joseph Murray, National Foundation for Celiac Awareness

August 14th, 2015 · Leave a Comment

Relatives, Spouses of Celiac Disease Patients at Risk for Autoimmune Disease

By Kanaaz Pereira Kanaaz Pereira

Mayo Clinic gastroenterologist and celiac disease expert, Joseph Murray, M.D., talks about a recent study published in Clinical Gastroenterology and Hepatology, which found that relatives and spouses of individuals with celiac disease are at an increased risk of non-celiac autoimmune diseases.

Read the full article online here.

For more information about celiac disease, visit mayoclinic.org/celiacdisease

Dr. Murray is a gastroenterologist at Mayo Clinic specializing in the care of patients with celiac disease.

Tags: autoimmune disease, celiac disease, Clinical Gastroenterology and Hepatology, Joseph Murray

August 3rd, 2015 · Leave a Comment

Mining for 'Gold' in Human Faeces

By Kanaaz Pereira Kanaaz Pereira

Mayo Clinic gastroenterologist and celiac disease expert Joseph Murray, M.D., discusses recent research, published in the American Journal of Gastroenterology, which examines the identification of a gluten-degrading enzyme as a potential novel treatment for celiac disease.

Researchers examined bacteria in stool samples of healthy people, and characterized enzymes made by bacteria that adapted to eat or degrade gluten. More importantly, these enzymes could work at an acidic pH to break down gluten.

New research, focusing on our microbiome is increasing, and there is hope that enzyme therapy can  be effective, and may offer relief to patients with celiac disease.

Read the full study online here.

For more information about celiac disease, visit mayoclinic.org/celiac disease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

 

Tags: American Journal of Gastroenterology, celiac disease, gluten, Joseph Murray, microbiome

July 20th, 2015 · 2 Comments

Increased Rates of Pregnancy Complications in Women with Celiac Disease

By Kanaaz Pereira Kanaaz Pereira

Mayo Clinic gastroenterologist and celiac disease expert Joseph Murray, M.D., discusses one of the largest women's health studies, published in the Annals of Gastroenterology that examines the risk of pregnancy complications in women with untreated celiac disease.

Although celiac disease is associated with intestinal disorder, it is important to note that that it can impact the reproductive health of women outside the digestive system. The study associated celiac disease with significant increases in spontaneous abortion, premature delivery, and later age of menarche.

Read the full study online here.

For more information about celiac disease, visit mayoclinic.org/celiac disease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Tags: Annals of Gastroenterology, celiac disease, Joseph Murray, pregnancy complications

July 3rd, 2015 · Leave a Comment

Diabetes and Gluten: What You Need to Know

By Kanaaz Pereira Kanaaz Pereira

Is gluten something you should avoid if you have diabetes? An article recently published in Healthline News explores the connection between gluten and diabetes. The article states:

  •  According to some research, there may be a genetic link between celiac disease and type 1 diabetes. However, there seems to be no connection between celiac disease and type 2 diabetes.
  • To streamline a diet, making it more diabetes-friendly, there are plenty of starchy foods that don't include gluten. Sweet and white potatoes, brown rice, wild rice, quinoa, beans, corn are great options.
  • Gluten-free products can be higher in added sugars or sodium, and many contain less fiber. This may cause carbohydrates to be more rapidly absorbed, which can spike blood sugar, so read food labels carefully.
  • "If you have diabetes and celiac disease, you absolutely should go gluten-free. It’s the only way to avoid the pain and damage caused by eating even a little gluten."

Read the full article online here.

For more information on celiac disease, visit mayoclinic.org/celiacdisease.

Tags: celiac disease, diabetes, gluten, Healthline News

May 15th, 2015 · Leave a Comment

Gluten-Free Recipe: Sauteed Bananas with Caramel Sauce

By Margaret Shepard Margaret Shepard

Looking for a healthy dessert for the weekend? Try sauteed bananas with caramel sauce!

Here's a tip from a Mayo Clinic dietitian: With a glaze of caramel sauce, this banana dish is a sweet ending to any dinner. Rich-flavored walnut oil lends an exotic accent. Apple juice is a good substitute for the rum in a nonalcoholic version.

Ingredients
For the sauce

1 tablespoon butter
1 tablespoon walnut oil (or canola oil)
1 tablespoon honey
2 tablespoons firmly packed brown sugar
3 tablespoons 1 percent low-fat milk
1 tablespoon dark raisins or golden raisins (sultanas)
4 firm bananas, about 1 pound total weight
1/2 teaspoon canola oil
2 tablespoons dark rum or apple juice

Directions
To make the sauce, in a small saucepan melt the butter over medium heat. Whisk in the walnut oil, honey and brown sugar. Cook, stirring continuously until the sugar is dissolved, about 3 minutes. Stir in the milk, 1 tablespoon at a time, and then cook, stirring continuously until the sauce thickens slightly, about 3 minutes. Remove from the heat and stir in the raisins. Set aside and keep warm.

Peel the bananas, and then cut each crosswise into 3 sections. Cut each section in half lengthwise. Lightly coat a large nonstick frying pan with the canola oil and place over medium-high heat. Add the bananas and saute until they begin to brown, 3 to 4 minutes. Transfer to a plate and keep warm.

Add the rum to the pan, bring to a boil and deglaze the pan, stirring with a wooden spoon to scrape up any browned bits from the bottom of the pan. Cook until reduced by half, about 30 to 45 seconds. Return the bananas to the pan to rewarm.

To serve, divide the bananas among individual bowls or plates. Drizzle with the warm sauce and serve immediately.

Tags: Friday recipe, Gluten Free, gluten free recipe, Healthy Living

April 30th, 2015 · Leave a Comment

Celiac Disease and Metabolic Syndrome

By Margaret Shepard Margaret Shepard

Joseph Murray, M.D., discusses a recently published article in the Alimentary Pharmacology & Therapeutics. The study addresses metabolic syndrome in patients with celiac disease.

Read the full study online here.

For more information about celiac disease, visit mayoclinic.org/celiacdisease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Tags: Alimentary Pharmacology Therapeutics, celiac disease, Joseph Murray, metabolic syndrome

Load More