Celiac Disease

Discussing the latest advances in celiac disease

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April 24, 2014

Bone Density and Celiac Disease

By Margaret Shepard, Communications Specialist

Joseph Murray, M. D., discusses a recently published article in the Indian Journal of Medical Research about bone diseases, a common complication of celiac disease.

Bone diseases associated with celiac disease are either osteoporosis or osteomalacia. Osteomalacia is due mainly to vitamin D and calcium deficiency where as osteoporosis may be multifactorial.

This study examined a small trial group of celiac disease patients that received two different standard therapies. One therapy was a gluten-free diet and a calcium D supplement. The second therapy was zoledronic acid, a bisphosphonate. The results show there is vast improvement in bone density in both groups within a twelve month follow up. The zoledronic acid improvement was not significantly different than the standard treatment in terms of improvement.

Bone disease is common and needs to be actively managed. A gluten-free along with supplements of vitamin D and calcium is the first line of treatment for bone disease. More aggressive or bone specific therapies are best reserved for secondary use.

Read the full study online here.

For more information on celiac disease, visit mayoclinic.org/celiacdisease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Tags: bone density, bone disease, celiac disease, Clinical Trials, Indian Journal of Medical Research, Joseph Murray, Study Findings, zoledronic acid


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