Celiac Disease

Discussing the latest advances in celiac disease

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July 10th, 2014

Celiac Disease and Brain Fog

By Margaret Shepard, Communications Specialist

Joseph Murray, M.D., discusses a recently published article in Alimentary Pharmacology & Therapeutics about brain fog and celiac disease.


For people with celiac disease, brain fog implies significant cognitive impairment. Brain fog indicates problems with thinking, memory, recall, and computation. Brain fog can lead to significant mental fatigue.

This recent study took place in Australia and closely followed a small group of patients with celiac disease. The researchers tested their mental ability with multiple tests at the time of diagnosis and at 12 and 52 weeks later. They also followed their symptoms with blood tests and biopsies. At 12 weeks, patients showed significant improvement in all of the measures, especially antibody tests and biopsies. Most interestedly, the patients showed a significant improvement in cognitive ability over time. This suggests that not only does celiac disease impair cognitive function but a gluten-free diet improves it.

More information and studies needs to be done on this subject of brain fog and how celiac disease impairs brain function. There's hope for patients with celiac disease that their cognitive function will improve once they are appropriately treated.

Read the full study online here.

For more information on celiac disease, visit mayoclinic.org/celiacdisease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Tags: Alimentary Pharmacology & Therapeutics, brain fog, celiac disease, cognitive impairment, Joseph Murray, Study Findings


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