Although celiac disease primarily affects the gut, the clinical spectrum of celiac disease is remarkably varied, and the disease can affect many extraintestinal organs, including the liver. Dr. Joseph Murray, M.D., reviews a study published in the World Journal of Gastroenterology, which identifies strategies for the diagnosis and treatment of these disorders in childhood.
Celiac disease is increasingly reported in children who are symptomless or present atypical symptoms and signs. As the medical community learns more about the far reaches of celiac disease, its association with liver ailments is receiving greater attention. Liver abnormalities can range from mild hepatic injury to severe liver disease. Although rarely, celiac disease may be also associated with severe liver involvement requiring liver transplant. All of these findings confirm the importance of early diagnosis and treatment of celiac disease-associated liver diseases.
Read the full study online here.
For more information about celiac disease, visit mayoclinic.org/celiac disease.
Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.