Celiac Disease

Discussing the latest advances in celiac disease

Clinical Trials

May 10th, 2016

New Drug Shows Promise for Celiac Patients

By Kanaaz Pereira kanaazpe

So far, treatment for celiac disease has been limited to a gluten-free diet, but as clinicians and researchers understand more about the causes of this disease, it has opened up many avenues for development of new treatment. There are at least 3 drugs that have shown hints of promise in small clinical trials, and larazotide acetate […]

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Tags: celiac disease, Joseph Murray, larazotide acetate, Phase-3 clinical trial


December 14th, 2015

The Strange World of Non-Celiac Gluten Sensitivity

By Kanaaz Pereira kanaazpe

We’ve all met people who say they can’t eat gluten, but don’t have celiac disease. If you’ve been wondering whether non-celiac gluten sensitivity is real, you’re not alone. The term non-celiac gluten sensitivity (NCGS) has been used to describe individuals who cannot tolerate gluten and experience symptoms similar to those with celiac disease, but yet lack the […]

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Tags: celiac disease, Clinical Gastroenterology and Hepatology, Joseph Murray, non-celiac gluten sensitivity


October 28th, 2015

A Review of Treatments Available for Celiac Disease

By Kanaaz Pereira kanaazpe

A gluten-free diet is central to the management of celiac disease, and has historically been the only treatment, although several potential therapies are now under development. In a paper published in Gastroenterology Reports, Dr. Joseph Murray, M.D., reviews the current landscape of new treatment approaches, and where these are in the development pipeline. Read the […]

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Tags: celiac disease, Gastroenterology Reports, gluten free diet, Joseph Murray, treatment


September 11th, 2015

Is Larazotide Acetate the Answer to Leaky Gut?

By Kanaaz Pereira kanaazpe

One of the early consequences of celiac disease is that the gut becomes permeable, allowing access of gluten molecules into the immune system. Dr. Joseph Murray, M.D., talks about the investigational drug, Larazotide Acetate, that was developed in a clinical trial to reduce this leakiness or permeability. The study has been published in Gastroenterology. Maintaining a […]

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Tags: celiac disease, Gastroenterology, gluten, Joseph Murray, larazotide acetate, leaky gut


July 17th, 2014

A Pill for Celiac Disease?

By Margaret Shepard, Communications Specialist Margaret_Marie

Joseph Murray, M.D., discusses a recently published article in Gastroenterology about a pill for the treatment of celiac disease.   For decades, celiac disease has been treated solely by a gluten-free diet. This proof-of-concept paper shows that a digestive enzyme engineered to specifically break down gluten proteins seems to be effective at preventing damage of […]

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Tags: AGA, celiac disease, enzyme, Gastroenterology, gluten free diet, Joseph Murray, pill


April 24th, 2014

Bone Density and Celiac Disease

By Margaret Shepard, Communications Specialist Margaret_Marie

Joseph Murray, M. D., discusses a recently published article in the Indian Journal of Medical Research about bone diseases, a common complication of celiac disease. Bone diseases associated with celiac disease are either osteoporosis or osteomalacia. Osteomalacia is due mainly to vitamin D and calcium deficiency where as osteoporosis may be multifactorial. This study examined […]

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Tags: bone density, bone disease, celiac disease, Indian Journal of Medical Research, Joseph Murray, zoledronic acid


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